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A New Marker For The Diagnosıs Of Sepsis: Presepsin

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman.

Cited by (3)

Abstract
Sepsis is a clinical syndrome that complicates severe infection. It is characterized by the cardinal signs of inflammation (vasodilatation, leukocyte accumulation, increased microvascular permeability) occurring in tissues which are remote from the infection. The clinical definitions of sepsis are basically nonspecific, often resulting in the delay of the diagnosis. During the last decade, a variety of different molecules have been suggested as clinical biomarkers in sepsis, most of which are still in experimental stage. However, some have came into use in clinical practice and have evolved as valuable tools for diagnosis, therapy monitoring, and outcome prediction.
Presepsin, which is approximately 13 kDa, has been identified as a protein whose levels increase specifically in the blood of sepsis patients. Presepsin is thought to be a more specific and sensitive marker for the diagnosis of sepsis compared with interleukin-6 and procalcitonin (PCT). Presepsin concentrations in blood were increased faster than PCT and CRP in sepsis patients. Although there are a lot of biomarkers to diagnose sepsis, presepsin could be a new candidate for this purpose. In this mini review, we discussed a new biomarker, presepsin, and its clinical relevance.

Key words: Presepsin, Sepsis, SIRS


 
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This Article Cited By the following articles


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How to Cite this Article
Pubmed Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. A New Marker For The Diagnosıs Of Sepsis: Presepsin. A J Physiol Biochem Pharmacol. 2012; 1(1): 55-57. doi:10.5455/jib.20120521073837


Web Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. A New Marker For The Diagnosıs Of Sepsis: Presepsin. http://www.ajpbp.com/?mno=18512 [Access: November 18, 2018]. doi:10.5455/jib.20120521073837


AMA (American Medical Association) Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. A New Marker For The Diagnosıs Of Sepsis: Presepsin. A J Physiol Biochem Pharmacol. 2012; 1(1): 55-57. doi:10.5455/jib.20120521073837



Vancouver/ICMJE Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. A New Marker For The Diagnosıs Of Sepsis: Presepsin. A J Physiol Biochem Pharmacol. (2012), [cited November 18, 2018]; 1(1): 55-57. doi:10.5455/jib.20120521073837



Harvard Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman (2012) A New Marker For The Diagnosıs Of Sepsis: Presepsin. A J Physiol Biochem Pharmacol, 1 (1), 55-57. doi:10.5455/jib.20120521073837



Turabian Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. 2012. A New Marker For The Diagnosıs Of Sepsis: Presepsin. American Journal of Physiology, Biochemistry and Pharmacology, 1 (1), 55-57. doi:10.5455/jib.20120521073837



Chicago Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. "A New Marker For The Diagnosıs Of Sepsis: Presepsin." American Journal of Physiology, Biochemistry and Pharmacology 1 (2012), 55-57. doi:10.5455/jib.20120521073837



MLA (The Modern Language Association) Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman. "A New Marker For The Diagnosıs Of Sepsis: Presepsin." American Journal of Physiology, Biochemistry and Pharmacology 1.1 (2012), 55-57. Print. doi:10.5455/jib.20120521073837



APA (American Psychological Association) Style

Mehmet Agilli, Irfan Sener, Fatih Yesildal, Tevfik Honca, Ibrahim Aydin, Emin Ozgur Akgul, Halil Yaman (2012) A New Marker For The Diagnosıs Of Sepsis: Presepsin. American Journal of Physiology, Biochemistry and Pharmacology, 1 (1), 55-57. doi:10.5455/jib.20120521073837





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