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Original Research 


Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus

Suresh Babu Kondaveeti, Ivvala Anand Shaker.

Abstract
Introduction: Since glycated albumin (GA) reflects with short term variations and these glycated protein shows degree of hyperglycemia, the objective of the study is to find GA and microalbuminuria as an early risk markers along with the duration of uncontrolled diabetes mellitus in type 2 diabetic nephropathy.
Materials and Methods: The present cross-sectional study included randomly selected uncontrolled type 2 DM [n=75], controlled type 2 DM [n=75] and healthy controls [n=75]. The fasting venous blood was obtained for GA and serum creatinine, while their morning urine sample was obtained for detection of microalbuminuria. Statistical analysis was done using SPSS version 16.0. One-Way ANOVA was performed. All p-values < 0.05 were considered as statistically significant.
Results: The mean GA, microalbuminuria and serum creatinine were the highest in uncontrolled DM when compared with controlled DM respectively. Microalbuminuria and GA had a significant correlation with duration of diabetes (p<0.0001).
Conclusion: The present study identifies that the risk of microalbuminuria increases with poor glycemic control. Persistent increase in GA and microalbuminuria may be considered as risk markers in diabetic nephropathy. Therefore, regular screening for microalbuminuria and GA estimation can help in clinical management to prevent complications.

Key words: Glycated albumin; microalbuminuria; diabetic nephropathy.


 
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How to Cite this Article
Pubmed Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. A J Physiol Biochem Pharmacol. 2013; 2(2): 127-131. doi:10.5455/jib.20130507061739


Web Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. http://www.ajpbp.com/?mno=36353 [Access: November 18, 2018]. doi:10.5455/jib.20130507061739


AMA (American Medical Association) Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. A J Physiol Biochem Pharmacol. 2013; 2(2): 127-131. doi:10.5455/jib.20130507061739



Vancouver/ICMJE Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. A J Physiol Biochem Pharmacol. (2013), [cited November 18, 2018]; 2(2): 127-131. doi:10.5455/jib.20130507061739



Harvard Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker (2013) Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. A J Physiol Biochem Pharmacol, 2 (2), 127-131. doi:10.5455/jib.20130507061739



Turabian Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. 2013. Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. American Journal of Physiology, Biochemistry and Pharmacology, 2 (2), 127-131. doi:10.5455/jib.20130507061739



Chicago Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. "Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus." American Journal of Physiology, Biochemistry and Pharmacology 2 (2013), 127-131. doi:10.5455/jib.20130507061739



MLA (The Modern Language Association) Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker. "Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus." American Journal of Physiology, Biochemistry and Pharmacology 2.2 (2013), 127-131. Print. doi:10.5455/jib.20130507061739



APA (American Psychological Association) Style

Suresh Babu Kondaveeti, Ivvala Anand Shaker (2013) Evaluation of glycated albumin and microalbuminuria as early risk markers of nephropathy in type 2 diabetes mellitus. American Journal of Physiology, Biochemistry and Pharmacology, 2 (2), 127-131. doi:10.5455/jib.20130507061739





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