Protective effects of a locally manufactured device on electromagnetic radiation-induced cellular alterations in rats exposed to mobile phone radiation

Abstract

Hussein Oyelola Bukoye Oloyede, Zakariyyau Atiq, Rilwan Adebayo Adigun, Musa Oyewole Salawu

Aim/Background: There is a worldwide concern on the possible health hazards induced by electromagnetic fields (EMFs) emitted by handheld devices and laptops. The present study, therefore, investigated the effect of a locally manufactured anti-electromagnetic radiation (EMR) device in rats exposed to mobile phone radiation. Methods: Thirty-two rats were acclimatized for 2 weeks and randomized into four groups; Group I was the control (not exposed to radiation or device) and Groups II-IV were exposed to phone only, device only, and phone and device, respectively. The rats were exposed to continuous EMFs for 1 h daily (totaling 50/missed calls) for 28 days. Results: EMF exposure caused a significant decrease (P < 0.05) in the activity of superoxide dismutase (SOD) and catalase (CAT) and also reduced glutathione (GSH) concentration, but a significant increase (P < 0.05) in alanine aminotransferase (ALT), aspartate transaminase, and malondialdehyde (MDA) concentrations, indicating lipid peroxidation. There was no significant difference (P > 0.05) between the rats exposed to the device only and those exposed to the mobile phone and the anti-EMR device when compared to the control. The histo-architecture assessment for the brain and liver also showed significant differences (P < 0.05) in organs of rats exposed to the mobile phone only when compared to the normal, the device only group, and the rats exposed to the anti-EMR device plus the mobile phone. From the study, the anti-EMR device was able to reverse the effect of mobile phone radiation on the SOD, CAT, ALT and aspartate aminotransferase activities, and reduced GSH and MDA concentrations. Conclusion: The locally manufactured anti-EMR device has anti-radiation capacity and reduced the threat posed by these EMRs in the rats